• Technical Conference & Exhibit:  01 – 04 November 2021
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Label-free Interferometric Scattering Imaging of Molecular Fluctuation Predicts Fluorescence Nuclear Microscope Images (JW7A.110)

Presenter: Yi-Teng Hsiao, Academia Sinica

We demonstrate a computational method to map the nuclear organization of live cells based on a deep-learning approach where the time-varying scattering signal is used to estimate the density of chromatin in the fluorescence image.

Authors:Yi-Teng Hsiao, Academia Sinica / Chia-Ni Tsai, Academia Sinica / Tsai-Ying Wu, Academia Sinica / Huan-Hsin Tseng, Academia Sinica / Yu Tsao, Academia Sinica / Chia-Lung Hsieh, Academia Sinica

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